1,725 research outputs found

    Assimilation of Earth rotation parameters into a global ocean model: excitation of polar motion

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    The oceanic contribution to Earth rotation anomalies can be manifold. Possible causes are a change of total ocean mass, changes in current speed or location and changes in mass distribution. To derive the governing physical mechanisms of oceanic Earth rotation excitation we assimilate Earth rotation observations with a global circulation ocean model. Before assimilation, observations of length of day and polar motion were transformed into estimates of ocean angular momentum. By using the adjoint 4D-VAR assimilation method we were able to reproduce these estimated time series. Although length of day was assimilated simultaneously the analysis in this paper focuses on the oceanic polar motion generation. Our results show that changes in mass distribution and currents contribute to oceanic polar motion generation. Both contributions are highly correlated and show similar amplitudes. The changes in the model done by the assimilation procedure could be related to changes in the atmospheric forcing. Since for geometrical reasons the change of total ocean mass does not project on polar motion, we conclude that the polar motion is mainly generated by a geostrophic response to atmospheric momentum forcing. In geostrophic currents mass displacement and current speed entail each other. This way the large similarity of mass and current generated ocean angular momentum can be explained

    Bottom-up assembly of functional intracellular synthetic organelles by droplet-based microfluidics

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    Bottom-up synthetic biology has directed most efforts toward the construction of artificial compartmentalized systems that recreate living cell functions in their mechanical, morphological, or metabolic characteristics. However, bottom-up synthetic biology also offers great potential to study subcellular structures like organelles. Because of their intricate and complex structure, these key elements of eukaryotic life forms remain poorly understood. Here, the controlled assembly of lipid enclosed, organelle-like architectures is explored by droplet-based microfluidics. Three types of giant unilamellar vesicles (GUVs)-based synthetic organelles (SOs) functioning within natural living cells are procedured: (A) synthetic peroxisomes supporting cellular stress-management, mimicking an organelle innate to the host cell by using analogous enzymatic modules; (B) synthetic endoplasmic reticulum (ER) as intracellular light-responsive calcium stores involved in intercellular calcium signalling, mimicking an organelle innate to the host cell but utilizing a fundamentally different mechanism; and (C) synthetic magnetosomes providing eukaryotic cells with a magnetotactic sense, mimicking an organelle that is not natural to the host cell but transplanting its functionality from other branches of the phylogenetic tree. Microfluidic assembly of functional SOs paves the way for high-throughput generation of versatile intracellular structures implantable into living cells. This in-droplet SO design may support or expand cellular functionalities in translational nanomedicine

    Improving a joint inversion of GRACE, GPS and modelled ocean bottom pressure by using in-situ data.

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    To investigate the changes in ocean bottom pressure (OBP) and ocean mass Rietbroek et al. (2009) performed a joint least square inversion of weekly GRACE solutions, patterns of large-scale deformation measured by a network of GPS stations and modelled OBP from the Finite Element Sea ice Ocean Model (FESOM). The correlation of this inversion with in-situ OBP ranges between 0.7 and 0.8 in some regions but for example in the tropical Atlantic the correlation is below 0.4. To improve the agreement of the inversion with in-situ data, a part of the in-situ data is included directly into the inversion. The in-situ OBP data was taken from the global OBP data base of Macrander et al. (2010) and averaged to weekly means. Depending on the weight put on the in-situ data, the correlation and regression increases significantly to a value larger than 0.9. The variance of the system is locally reduced by almost 50% at the locations included into the inversion while the difference of the global ocean mean is on average below 10%. Furthermore the global ocean mean is used to compute a bias term for correcting the global ocean mean obtained by the FESOM model

    A Characterisation of the Weylian Structure of Space-Time by Means of Low Velocity Tests

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    The compatibility axiom in Ehlers, Pirani and Schild's (EPS) constructive axiomatics of the space-time geometry that uses light rays and freely falling particles with high velocity, is replaced by several constructions with low velocity particles only. For that purpose we describe in a space-time with a conformal structure and an arbitrary path structure the radial acceleration, a Coriolis acceleration and the zig-zag construction. Each of these quantities give effects whose requirement to vanish can be taken as alternative version of the compatibility axiom of EPS. The procedural advantage lies in the fact, that one can make null-experiments and that one only needs low velocity particles to test the compatibility axiom. We show in addition that Perlick's standard clock can exist in a Weyl space only.Comment: to appear in Gen.Rel.Gra

    Optical bistability in subwavelength apertures containing nonlinear media

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    We develop a self-consistent method to study the optical response of metallic gratings with nonlinear media embedded within their subwavelength slits. An optical Kerr nonlinearity is considered. Due to the large E-fields associated with the excitation of the transmission resonances appearing in this type of structures, moderate incoming fluxes result in drastic changes in the transmission spectra. Importantly, optical bistability is obtained for certain ranges of both flux and wavelength.Comment: 4 pages, 4 figure

    Potential Energy Surface for H_2 Dissociation over Pd(100)

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    The potential energy surface (PES) of dissociative adsorption of H_2 on Pd(100) is investigated using density functional theory and the full-potential linear augmented plane wave (FP-LAPW) method. Several dissociation pathways are identified which have a vanishing energy barrier. A pronounced dependence of the potential energy on ``cartwheel'' rotations of the molecular axis is found. The calculated PES shows no indication of the presence of a precursor state in front of the surface. Both results indicate that steering effects determine the observed decrease of the sticking coefficient at low energies of the H_2 molecules. We show that the topology of the PES is related to the dependence of the covalent H(s)-Pd(d) interactions on the orientation of the H_2 molecule.Comment: RevTeX, 8 pages, 5 figures in uufiles forma

    The quality of life after liver transplantation

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    The quality of life after liver transplantation ranges from poor to superior. The social and vocational outcome is dependent on the quality of homograft function and on the steroid doses necessary to maintain function. A good long-term prognosis is usually evident by 1 year postoperatively. The complete rehabilitation of so many patients has encouraged us to continue our efforts in this difficult field

    Liver transplantation - 1978

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    The development of liver transplantation has been made difficult because of the enormous technical difficulties of the procedure and because the postoperative management in early cases was defective in many instances. With surgical and medical improvements, the prospects for success have markedly increased recently. The wider use of thoracic duct fistula as an adjuvant measure during the first 1 or 2 postoperative months is being explored
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